A cellular automaton model of Glioblastoma Multiforme growth and immunotherapy treatment

  • Maverick Malaluan Juanico Department of Physical Sciences and Mathematics, University of the Philippines Manila
  • Herbert Boras Domingo Department of Physical Sciences and Mathematics, University of the Philippines Manila
  • Ramon Jose Cavitana Bagunu Department of Physical Sciences and Mathematics, University of the Philippines Manila

Abstract

Glioblastoma Multiforme (GBM) is a type of brain tumor that remains to be a lethal disease with a short survival time. Here, the proliferation of GBM tumor growth was simulated using cellular automaton (CA) model and was extended to simulating an immunotherapy treatment. Three different treatment durations were used to investigate the effects of different treatment rates on tumor growth. High rate treatment for a short time reduced proliferative activity, but did not fully eradicate the tumor. Medium and low rates for longer times were more successful in eliminating the tumor, with the low rate being more effective giving shorter time for tumor elimination.

Published
2019-05-22
How to Cite
[1]
M. Juanico, H. Domingo, and R. J. Bagunu. A cellular automaton model of Glioblastoma Multiforme growth and immunotherapy treatment, Proceedings of the Samahang Pisika ng Pilipinas 37, SPP-2019-PB-27 (2019). URL: https://paperview.spp-online.org/proceedings/article/view/SPP-2019-PB-27.